fetal alcohol syndrome in fetus of mouse
نویسندگان
چکیده
litis study is based on embryotoxic effects of ethanol on embryos and discussing the morphologic and hhtahtgic changes and defects an mouse. tlie female animals were divided in three groups. hie first group untreated as a control group but the second and third group received 10% and 20% solutions of ethanol respectively. animals get use to certain level of ethanol solution and in the 10th day, the pregnancy period has been started. then on the 19th day of gestation, the embryos were taken out from their mother's uterus and were examined for morphologic, histologic and skeletal disorders. in the first examination, the major defect was weight and length reduction in the second and third groups. these deffects, were severe in the second group in compare to third group that might be related to little consumption of the ethanol solution, due to bitter taste. in conclusion the teratogenic effect of alcohol on skeleton and joint is clear.
منابع مشابه
Fetal Alcohol Syndrome
Background: About 40 thousand newborns are delivered annually with fetal alcohol syndrome (FAS). It induces serious CNS complications. Methods: In a review of, the word “fetal alcohol syndrome” was searched in PubMed and Google Scholar and the retrieved articles were summarized. Results: Many studies showed that alcohol can cause more defects in fetus than heroin, cocaine and marijuana. The pos...
متن کاملPrevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome.
Two peptides [NAPVSIPQ (NAP) and SALLRSIPA (ADNF-9)], that are associated with novel glial proteins regulated by vasoactive intestinal peptide, are shown now to provide protective intervention in a model of fetal alcohol syndrome. Fetal demise and growth restrictions were produced after intraperitoneal injection of ethanol to pregnant mice during midgestation (E8). Death and growth abnormalitie...
متن کاملFetal alcohol syndrome
Alcohol is a physical and behavioural teratogen. Fetal alcohol syndrome (FAS) is a common yet un der-recognized condition resulting from maternal consumption of alcohol during pregnancy. While preventable, FAS is also disabling. Although FAS is found in all socioeconomic groups in Canada, it has been observed at high prevalence in select First Nations and Inuit communities in Canada. This stat...
متن کاملFetal alcohol syndrome
Alcohol is a physical and behavioural teratogen. Fetal alcohol syndrome (FAS) is a common yet under-recognized condition resulting from maternal consumption of alcohol during pregnancy. While preventable, FAS is also disabling. Although FAS is found in all socioeconomic groups in Canada, it has been observed at high prevalence in select First Nations and Inuit communities in Canada. This statem...
متن کاملFetal Alcohol Syndrome
Alcohol use by a pregnant woman may interfere with the development of her fetus. Newborns whose mothers are intoxicated during delivery can experience withdrawal symptoms, such as tremors and even seizures. It is likely that withdrawal also can occur during fetal development. Thus, the possibility exists that withdrawal by the pregnant woman may exacerbate alcohol’s adverse effects on her fetus...
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عنوان ژورنال:
acta medica iranicaجلد ۳۵، شماره ۳-۴، صفحات ۶۳-۶۸
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